Studienergebnisse von Frieda Menova
Question
Does individualized perioperative blood pressure management based on preoperative nighttime mean arterial pressure (MAP) improve outcomes in patients undergoing abdominal surgery who are considered at high risk of postoperative complications?
Conclusions and Relevance
Among patients at high risk of postoperative complications undergoing major abdominal surgery, individualized perioperative blood pressure management with MAP targets based on preoperative mean nighttime MAP did not decrease the composite outcome of acute kidney injury, acute myocardial injury, nonfatal cardiac arrest, or death within the first 7 postoperative days compared with routine blood pressure management with a MAP target of 65 mm Hg or higher.
Location
15 university hospitals in Germany
Population
Adults 45 years or older undergoing elective abdominal surgery with general anesthesia expected to last 90 minutes or longer
Men: 747
Women: 356
Median age: 66 years
Intervention
571 with invidiualised management: dashjdhajdhsajdhasjdhadaskj
571 with routine management: dasdsakdkashd kashdk asd sa
Primary outcome
Incidence of a composite outcome dahsjd hsajh djashd jshjas h kadshdksah dksahd kashd kasd hkasd haksd haksdh kasd haskd ahksd hsakdh kasd hkashdkashd kash dkashhd kashd kasdhkashdka s.
Findings
Invidiualised management: dashjdhajdhsajdhasjdhadaskj
Routine management: dasdsakdkashd kashdk asd sa
There was no statistically signigcant difference between groups:
-
Absolute difference: 3.00% (95% CI, 2,61% to 8,60%)
-
Relative risk: 1.10 (95% CI, 2,61% to 8,60%); P=.31
Source
Link to publication.